Analysis demonstrates a link between B7-H3 expression and oncogenic pathways in various tumors, suggesting therapeutic potential.
Association of B7-H3 expression and common hallmark mRNA signatures. GSEA with functional oncogenic pathways on several tumor types with high and low B7-H3 expression. Normalized enrichment scores are displayed. FDR < 0.05 based on values between −3 and 3. Boxes marked with “X” indicate that the enrichment of the pathway did not meet thresholds of significance in the tumor type.
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Miller et al. (2024) studied this question.
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