Analysis of B7-H3 expression identifies potential therapeutic targets across various malignancies, suggesting broader implications for treatment.
Characterization of B7-H3 expression in tumors. B7-H3 transcripts per million (TPM) after log normalization. A total of 156,791 samples from 50 distinct tumor types were analyzed from the Precision Oncology Alliance (POA) consortium. Data shown in violin plots in which the white dot represents the median and the black box shows the ends of the first and third quartiles. The female genital tract malignancy category represents sarcomas from gynecologic sites and the male genital tract malignancy category represents primarily testicular cancer.
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Miller et al. (2024) studied this question.
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