Relationship Between Red Blood Cell Distribution Width and No-Reflow In ST-Elevation Myocardial Infarction patients Undergoing Primary Percutaneous Coronary Intervention

Objective: To find the association between Red Blood Cell Distribution Width (RDW) and the incidence of no-reflow in ST-Elevation Myocardial Infarction patients treated with Primary Percutaneous Coronary Intervention. Study Design: Analytical Cross-sectional study. Place and Duration of Study: At Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi Pakistan, from Aug 2023 to Feb 2024. Methodology: Total one hundred and thirty-nine patients who underwent Primary Percutaneous Coronary Intervention within 24 hours of symptoms onset were enrolled via consecutive sampling for study purpose. RDW values were noted from Complete Blood Count conducted upon the patients' arrival at the emergency department. Thrombolysis in Myocardial Infarction grading system was utilized to assess the scale of blood flow during angiography. On the basis of mean RDW value, participants were categorized into two groups: Group-I=RDW<14 and Group-II=RDW≥14. Receiver Operating Characteristics curve was generated to evaluate the predictive capability of RDW values for identifying cases of no-reflow. The association of study variables with RDW was assessed by applying Chi-square test, and significance level was set at p<0.05. Results: Out of 139 participants, 118(84.9%) were males and 21(15.1%) were females. The mean age of study sample was 61.75±10.91 years. 64(46.0%) patients were present in RDW<14 group and 75(53.9%) in RDW≥14 group. Out of 64, the incidence of No Reflow Phenomenon (NRP)/slow flow was 28(43.8%) in Group-I while in Group-II, it was ............ Conclusion: RDW does not independently predict no-reflow.............