Key result
STEMI is linked to ~4-point lower mean LVEF compared to NSTEMI.
Why the study?
The study aimed to determine and compare LVEF and associated factors in STEMI and NSTEMI patients and to assess early hospital outcomes after AMI.
Observational (n=178)
No
Absolute Event Rate: 43.77% vs 47.49%
p-value: p=0.03
Echocardiographic assessment reveals that STEMI patients have significantly lower LVEF than NSTEMI patients, and severely reduced LVEF correlates with worse early in-hospital outcomes.
May identify higher-risk STEMI patients for monitoring; extends observational data on LVEF by infarct type.
Objective: To determine and compare Left Ventricular Ejection Fraction (LVEF) and its associated factors in STEMI and NSTEMI patients and to determine early hospital outcomes in STEMI and NSTEMI patients. Study Design: Prospective observational study Place and Duration of Study: Mardan Medical Complex, Mardan, Pakistan, from Sep 2024 to Feb 2025. Methodology: A total of 178 research participants diagnosed and admitted with AMI (89 STEMI & NSTEMI each) of both genders were included. Data was collected using a predesigned questionnaire after informed consent and echocardiographic evaluation of left ventricular ejection fraction (LVEF%). Conventional risk factors were confirmed from history/investigations, and in-hospital outcomes were considered post-AMI consequences during patients' hospital stay. Data was analyzed using SPSS. Results: Out of the total 178 patients, 57.30% were male. The mean age was 57.52 + 10.26 years. The mean LVEF (%) among STEMI & NSTEMI patients was 43.77 + 10.75 & 47.49 + 12.15, respectively. Mild and moderate LV systolic dysfunction was common among STEMI, while severe among NSTEMI. Obesity and diabetes were more common among females. Pericardial effusion, MR, and cardiogenic shock were more common among STEMI. Patients with heart failure, MR, cardiac arrest, and death had significantly (p < 0.05) reduced mean LEVF%. Conclusion: Mean LVEF% was lower among STEMI, and in-hospital outcomes were higher with severely reduced ejection fraction. Transthoracic echocardiography can provide information on short- and long-term outcomes after AMI. Regular Echocardiography is advised, which guides management, improves prognosis, and reduces other complications.
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Ali et al. (2026) conducted an observational in Acute Myocardial Infarction (STEMI and NSTEMI) (n=178). ST-Elevation Myocardial Infarction (STEMI) vs. Non-ST-Elevation Myocardial Infarction (NSTEMI) was evaluated on Mean Left Ventricular Ejection Fraction (LVEF%) (p=0.03). ST-segment elevation myocardial infarction was associated with a significantly lower mean left ventricular ejection fraction (43.77%) compared to non-ST-segment elevation myocardial infarction (47.49%).
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