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May 29, 2024Communications MedicineOpen Access

Identifying multi-resolution clusters of diseases in ten million patients with multimorbidity in primary care in England

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Authors

TBThomas BeaneyJCJonathan ClarkeDSDavid Salman

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Overview

Observational study reveals multi-resolution disease clusters in primary care patients, highlighting structured co-occurrence patterns across multimorbidity.

Key Points

  • Markov multiscale community detection outperforms k-means across 253 known disease pairs, uncovering almost-hierarchical disease clusters.
  • Analysis of primary care records extracts representations of 212 conditions across ten million patients using skip-gram and co-occurrence models.
  • Supports future discovery of novel disease associations from electronic health records, facilitating targeted clinical management of multimorbidity.

Cite This Study

Beaney et al. (2024) studied this question.

synapsesocial.com/papers/68e67cc7b6db643587606e4chttps://doi.org/10.1038/s43856-024-00529-4
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