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May 27, 2024Lipids in Health and DiseaseOpen Access

A cross-sectional analysis of the relationship between the non-high density to high density lipoprotein cholesterol ratio (NHHR) and kidney stone risk in American adults

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Authors

YDYuan-Zhuo DuNanchang UniversityQDQian-Xi DongNanchang UniversityHHHong-Ji HuNanchang University

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Overview

Cross-sectional study finds elevated non-high density to high density lipoprotein cholesterol ratios increase kidney stone risk in adults, highlighting its utility as a metabolic risk biomarker.

Key Points

  • Higher non-high density to high density lipoprotein cholesterol ratio levels track increased kidney stone risk, displaying a non-linear correlation across patient subgroups (P < 0.001).
  • Cross-sectional analysis of National Health and Nutrition Examination Survey data from 2007 to 2018 utilized weighted logistic regression and restricted cubic spline models in adults over 20.
  • Highlights the clinical value of the NHHR metric as an accessible circulating biomarker for kidney stone formation, which may aid preventive screening for related metabolic disorders.

Cite This Study

Du et al. (2024) studied this question.

synapsesocial.com/papers/68e6836bb6db64358760c10chttps://doi.org/10.1186/s12944-024-02150-9
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