32 Comparisons of accelerometer-assessed physical activity, inactivity and sleep in individuals with hypertrophic cardiomyopathy versus individuals with heart failure

Introduction Engagement in regular physical activity reduces symptom burden and improves quality of life in individuals with hypertrophic cardiomyopathy (HCM) and those living with heart failure (HF). This study evaluated the physical activity, inactivity and sleep of individuals living with HCM versus individuals living with HF. Methods Twenty-one individuals with HCM (52±15 years old, body mass index (BMI) 29 (26–31) kg/m2) and eighteen individuals with stable chronic HF with reduced ejection fraction (68±7 years old, BMI: 27 (25–31) kg/m2, left ventricular ejection fraction: 35 (30–35) %) completed 7-day monitoring using wrist-worn triaxial accelerometers (GENEActiv, ActivInsights Ltd, UK). Results described as median (interquartile range). Results After controlling for age, time spent in 1–5 minute bouts of light intensity physical activity were greater in individuals with HCM versus individuals with HF (45 (24–55) vs. 37 (25–46 minutes/day, p=0.02). Steps/day were similar for individuals with HCM versus HF (9762 (7755–12496 vs. 8138 (7174–11257) steps/day, p=0.72). There were no other significant differences in physical activity, inactivity or sleep variables between the two groups. Age was significantly negatively correlated with time spent in 10-minute bouts of moderate-vigorous physical activity (r=-0.61, p<0.01) but positively correlated with time spent in 10-minute bouts of light physical activity (r=0.44, p<0.05) in individuals with HCM only. Peak oxygen consumption was positively correlated with moderate-vigorous physical activity for both individuals with HCM (r=0.56, p<0.05) and HF (r=0.52, p<0.05). Conclusions Individuals with HCM spend greater periods in light bouts of physical activity compared to individuals with HF but no differences were found for the other accelerometery parameters. Advanced ageing has a stronger negative effect on time spent in moderate-vigorous physical activity in individuals with HCM. Individuals in both groups should be encouraged to participate in bouts of both light and moderate-vigorous physical activity to benefit health. Conflict of Interest N/A