Lack of Association of Mitochondrial tRNA(Leu) A3243G Mutation with Allergic Chronic Rhinosinusitis Pathogenesis in South Indian Population

The association between genetic variants and respiratory conditions such as allergy and chronic rhinosinusitis has been the subject of extensive research. While the mitochondrial tRNA A3243G mutation has been extensively studied in the context of mitochondrial disorders, its potential role in inflammatory conditions such as allergy and chronic rhinosinusitis is not as well understood. In this study, we aim to explore and understand the potential link between the mitochondrial tRNA A3243G mutation and the prevalence of allergic CRS.