Enantioselective Crystallization of Naturally Chiral Ag₂CO₃ Crystals Insights into the Influence of Chiral Additives

Chiral induction of chiral crystals attracts significant attention due to its implications for developing chiral materials and understanding mechanisms of symmetry breaking enantioselective crystallization of naturally chiral inorganic crystals and their potential use in chiral discrimination, which are, however, largely unexplored. Here, we investigate the chiral induction during the crystallization of naturally chiral Ag2CO3 crystals using arginine amino acid as the chiral inducer. The chiral nature of Ag2CO3 was evaluated using various techniques. Chiral crystals exhibited chiral selective binding toward different amino acid enantiomers. The significant selectivity in adsorption was confirmed by circular dichroism, high-performance liquid chromatography, and isothermal titration calorimetry. Understanding chiral induction in crystal growth may open avenues for the controlled assembly of chiral materials and the development of novel functional materials with unique properties.