May 2, 2024Cancer Research

Abstract PO4-19-04: AXSANA – EUBREAST-3: An international prospective multicenter cohort study to evaluate different surgical methods of axillary staging in clinically node-positive breast cancer patients treated with neoadjuvant chemotherapy

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The AXSANA trial evaluates surgical de-escalation of axillary staging in node-positive breast cancer patients who achieve clinically negative nodal status after chemotherapy.
Among 3722 patients with defined surgical concepts, targeted axillary dissection was scheduled in 1631 women, axillary lymph node dissection in 1483, and sentinel biopsy in 469.
International prospective cohort study enrolled 4336 patients across 284 sites to assess invasive disease-free survival, axillary recurrence, and quality of life over 5 years.

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Prospective cohort study analyzes axillary staging strategies in breast cancer patients converting to node-negative status after neoadjuvant chemotherapy, highlighting surgical de-escalation.

Cite This Study

Kühn et al. (2024) studied this question.

synapsesocial.com/papers/68e6be8eb6db64358763e35f https://doi.org/10.1158/1538-7445.sabcs23-po4-19-04

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Implication

Prospective cohort study analyzes axillary staging strategies in breast cancer patients converting to node-negative status after neoadjuvant chemotherapy, highlighting surgical de-escalation.

Abstract PO4-19-04: AXSANA – EUBREAST-3: An international prospective multicenter cohort study to evaluate different surgical methods of axillary staging in clinically node-positive breast cancer patients treated with neoadjuvant chemotherapy

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Discussion

Implication

Cite This Study

Abstract PO4-19-04: AXSANA – EUBREAST-3: An international prospective multicenter cohort study to evaluate different surgical methods of axillary staging in clinically node-positive breast cancer patients treated with neoadjuvant chemotherapy

Key Points

Discussion

Implication

Cite This Study

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