Biotin is a water-soluble vitamin necessary for metabolism of fatty acids, glucose, and amino acids to be used as energy for the body. Recommended daily intake of biotin for adults is up to 100 mcg daily. Daily multivitamins contain biotin doses of about 30 mcg. Hair, skin, nail vitamins can have doses reaching up to 10,000 mcg. There is an established association of biotin with thyroid hormone measurements leading to false elevations of free T4 and free T3 and low levels of thyroid stimulating hormone.
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Patel et al. (2024) studied this question.
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