May 1, 2024Physiology

High altitude sojourn elicits divergent effects in aortic and carotid stiffness in healthy-young adults

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Authors

SRSpencer RomanowskiIowa State University ABA BurkhartIowa State University CSCarolyn R. SteffenNational Institute of Standards and Technology

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Implication

Observational study shows divergent changes in aortic and carotid stiffness in healthy young adults, suggesting distinct regional vascular adaptations to hypoxia.

Key Points

Ascent to high altitude increases aortic stiffness while decreasing carotid stiffness despite concurrent elevations in mean arterial pressure in healthy adults.
Pulse wave velocity increased by 54.98 cm/s following high-altitude ascent, whereas arterial oxygen saturation simultaneously dropped by 11% across all subjects.
Assessment using applanation tonometry suggests that carotid dilation helps maintain cerebral perfusion despite systemic reductions in arterial oxygen saturation.

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Romanowski et al. (2024) studied this question.

synapsesocial.com/papers/68e6c6ecb6db643587645792 https://doi.org/10.1152/physiol.2024.39.s1.922

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Implication

Observational study shows divergent changes in aortic and carotid stiffness in healthy young adults, suggesting distinct regional vascular adaptations to hypoxia.

High altitude sojourn elicits divergent effects in aortic and carotid stiffness in healthy-young adults

Discussion

Member takes

Implication

Key Points

Cite This Study

High altitude sojourn elicits divergent effects in aortic and carotid stiffness in healthy-young adults

Discussion

Member takes

Implication

Key Points

Cite This Study

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