Background: Primary hyperparathyroidism due to parathyroid adenomas is the most common cause of hypercalcemia in otherwise healthy adults. Up until recent advances in preoperative imagining, excision of these adenomas required bilateral exploration of the neck. With the advent of preoperative imaging, and intraoperative parathyroid assay, a minimally invasive approach is now used. Dual-isotope simultaneous subtraction imaging, while not yet in widespread use, is a novel technique with promising results. This study aims to determine the increase in accuracy in identifying the location of parathyroid adenomas with the dual-tracer simultaneous-acquisition method compared with the single-tracer, dual-phase protocol that is currently predominant.
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O’Flynn et al. (2024) studied this question.
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