Risk Factors Analysis and Probability of Uncontrolled Hypertension on Chronic Kidney Disease Patients in Karawang

Background: Uncontrolled Hypertension has been highly prevalent recently. Controlling hypertension in Chronic Kidney Disease (CKD) patients is important to decrease morbidity and mortality. According to the International Society of Hypertension (ISH) Guideline 2020, CKD patients with blood pressure ≥140/90 mmHg should be treated to achieve a target blood pressure of <130/80 mmHg (<140/80 in elderly patients). Several risk factors have been identified as being associated with uncontrolled hypertension. Objective: To determine the prevalence, probability and analyze risk factors of uncontrolled hypertension in CKD patients. Method: This research is a cross-sectional study. Subjects were patients aged >18 years who have been diagnosed with CKD or with e GFR <60 mL/minute/1.73 m2 for at least 3 months at Karawang Regional Public Hospital using consecutive sampling. Laboratory data is taken based on medical records and interviewed with a questionnaire for identified risk factors, and adherence to taking medication using a Morisky Score (MMAS-8) questionnaire. Risk factor analysis used logistic regression with a significance level of p<0.05. Results: The prevalence of uncontrolled hypertension in CKD patients was 66,3%. Factors that significantly associated with uncontrolled hypertension on CKD was the gender factor, men have higher risk than women (OR=5,360;95% CI:1,672-17,190; p=0,003), salty food consumption (OR=10,490;95% CI:3,719-29,583; p=0,000), and medication adherence (OR=12,659;95% CI= 4,469-35,864; p=0,000). Based on the regression model, the probability was 99.96%. Conclusion: Factors that were significantly associated with the prevalence of uncontrolled hypertension in CKD patients were gender, salty food consumption, and medication adherence with a probability of 99,96%.