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December 1, 2023BMJ OpenOpen Access

Uncontrolled hypertension was present in 58.3% of hypertensive patients with early CKD and was significantly associated with alcohol use (OR 11.21), non-adherence (OR 10.19), and age ≥50 (OR 5.17).

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Why the study?

The study was conducted to determine the prevalence of uncontrolled hypertension and its associated factors among patients with early chronic kidney disease attending medical outpatient clinics at tertiary hospitals in Dodoma, Tanzania.

Population

352 adult patients with early CKD (stages 1, 2, and 3) in Dodoma, Tanzania

Design

Cross-sectional study across two tertiary hospitals

Key result

Uncontrolled hypertension was present in 58.3% of hypertensive patients with early CKD and was significantly associated with alcohol use (OR 11.21), non-adherence (OR 10.19), and age ≥50 (OR 5.17).

Authors

DKDenis D. KatatwireAMAlfred Meremo

Discussion

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Overview

High uncontrolled hypertension prevalence signals need for adherence support and alcohol reduction; leaves open causal effects and intervention trials in early CKD.

Study Design

Type

Cross-Sectional (n=352)

Multicenter

Yes

Structured PICO

P
Population
352 adult patients with early CKD stages 1-3 attending outpatient clinics at two tertiary hospitals in Tanzania.
O
Outcome
Uncontrolled hypertension based on blood pressure measurementssurrogate

Main Result

Odds Ratio: 11.21 (95% CI 3.83–32.84)

p-value: p=0.001

Uncontrolled hypertension is highly prevalent (58.3%) among patients with early CKD in Tanzania and is strongly associated with modifiable factors such as non-adherence, alcohol use, and obesity.

Cite This Study

Katatwire et al. (2023) conducted a cross-sectional in early chronic kidney disease (CKD) (n=352). Alcohol use vs. No alcohol use was evaluated on Uncontrolled hypertension (OR 11.21, 95% CI 3.83-32.84, p=0.001). Uncontrolled hypertension was present in 58.3% of hypertensive patients with early CKD and was significantly associated with alcohol use (OR 11.21), non-adherence (OR 10.19), and age ≥50 (OR 5.17).

synapsesocial.com/papers/6a98bbba3c2ace4a27748602https://doi.org/10.1136/bmjopen-2023-074441
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