Cold Autoimmune Hemolytic Anemia as First Clinical Manifestations in Systemic Lupus Erythematosus (SLE) in Young Female Patient, a Rare Association: Case Report

Background: Cold autoimmune hemolytic anemia” is very uncommon in systemic lupus erythematous (SLE), and until now a small number of similar reports have been published in scientific papers. Case presentation: Here, we present a nineteen-year-old female patient who admitted with cold type hemolytic anemia, pancytopenia and was later diagnosed to have SLE. Conclusion: Despite the very rare association between SLE and cold autoimmune hemolytic anemia (AIHA), this case report improves clinical practice regarding considering SLE as one of the differential diagnoses in cold AIHA, to provide early diagnosis and optimal management.