Corpus callosum lipoma is a very rare congenital malformation, which may be associated with varying degrees of corpus callosum dysgenesis. It is often asymptomatic but may present with epilepsy, hemiplegia, dementia, or simple headache. We report the case of a 48-year-old adult, followed for psychomotor retardation since childhood, who presented with epileptic seizures and was found to have a lipoma of the corpus callosum. Symptoms and prognosis depend on the associated malformation. MRI is the imaging modality of choice for diagnosis. Treatment is symptomatic: antiepileptic drugs in the event of epileptic seizures, and surgery is rarely indicated.
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Baderddine et al. (2024) studied this question.
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