Prevalence of glucometabolic abnormalities in Patients with Acute Coronary Syndrome Without Previously Known Diabetes

Background Patients with diabetes have an increased morbidity from acute myocardial infarction. The objective of this study was to characterize the glucometabolic profile during the hospital phase of patients with acute coronary syndrome without known of diabetes mellitus Methods A total of 80 patients with acute coronary syndrome and no previous diagnosis of diabetes. Patients consecutively admitted with acute coronary syndrome (ACS) in cerrahpasa faculty of medicine - coronary care unit were included. Glucometabolic status evaluated by a 75-g oral glucose tolerance test (OGTT) performed 5-10 days after admission of an ACS. Plasma glucose was measured at fasting, 60 minutes and 120 minutes after glucose load. Results The mean age was 58±13 years. Based on the OGTT, they were defined as having normal glucose tolerance (NGT; n = 31, 39%), impaired glucose tolerance (IGT; n = 28, %35), or diabetes (n = 21, %26). Conclusion The prevalence of abnormal glucose metabolism in patients with ACS is high. About 61% of the patients with ACS had undiagnosed impaired glucose tolerance or diabetes, as determined by an oral glucose tolerance test. The test could easily be performed shortly after diagnosis of ACS in all patients.