Key result
An oral glucose tolerance test identified abnormal glucose metabolism in 79% of hyperglycaemic patients with ACS, whereas APG, FPG, and HbA1c had low predictive value (AUC 0.61, 0.75, and 0.72).
Why the study?
Do APG, FPG, or HbA1c adequately predict undiagnosed diabetes compared to OGTT in hyperglycaemic patients with ACS?
Population
130 patients with acute coronary syndrome and elevated admission plasma glucose from the BIOMArCS 2 glucose…
Comparison
Admission plasma glucose, fasting plasma… vs Oral glucose tolerance test prior to discharge
Design
Cohort
Authors
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OGTT may detect undiagnosed diabetes in ACS with elevated APG; leaves open whether routine use improves outcomes.
Cross-Sectional (n=130)
Do APG, FPG, or HbA1c adequately predict undiagnosed diabetes compared to OGTT in hyperglycaemic patients with ACS?
In hyperglycaemic patients with ACS, APG, FPG, and HbA1c have low sensitivity for detecting undiagnosed diabetes, making OGTT the preferred diagnostic test prior to discharge.
Mulder et al. (2011) conducted a cross-sectional in Acute coronary syndrome with elevated admission plasma glucose (n=130). Oral glucose tolerance test (OGTT) vs. Admission plasma glucose, fasting plasma glucose, or HbA1c was evaluated on Detection of undiagnosed diabetes. An oral glucose tolerance test identified abnormal glucose metabolism in 79% of hyperglycaemic patients with ACS, whereas APG, FPG, and HbA1c had low predictive value (AUC 0.61, 0.75, and 0.72).
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