Incorporation of hydroxyapatite and cerium oxide nanoparticle scaffold as an antibacterial filler matrix for biomedical applications

Managing bone healing is essential for preventing problems such as non-union, bacterial infection, structural instability, psychological, and physical damage in patients. The need to use antibiotics less often has prompted researchers to look at possible substitutes, such as nanoparticles. In this investigation, we choose to employ cerium oxide nanoparticles due to their unique antibacterial properties based on redox reactions. The cerium oxide-hydroxyapatite composite was synthesized, calcined, and ball-milled to create a fine CeO