April 25, 2024Open Access

Mechanisms of Male Reproductive Sterility Triggered by Dysbiosis of Intestinal Microorganisms

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Male reproductive infertility is driven by gut microbiota dysbiosis, which compromises healthy testicular growth and disrupts essential endocrine regulation across tissues.
Narrative review of physiological pathways shows that microbial imbalances alter immune cell metabolism and disrupt the gut-brain-reproductive axis, hindering sperm production.
Highlights the necessity of targeting the gut-brain-reproductive axis to mitigate male reproductive infertility, and provides actionable recommendations for clinical prevention.

Authors

MWMingbang WeiXizang Minzu University HLHuaizhi LiuTibet University YWYu WangCentral South University

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Implication

Narrative review reveals gut microbiota dysbiosis impairs spermatogenesis and endocrine function in males, highlighting microbial pathways in reproductive sterility.

Cite This Study

Wei et al. (2024) studied this question.

synapsesocial.com/papers/68e6d980b6db643587655df8 https://doi.org/10.20944/preprints202404.1553.v1

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Implication

Narrative review reveals gut microbiota dysbiosis impairs spermatogenesis and endocrine function in males, highlighting microbial pathways in reproductive sterility.

Mechanisms of Male Reproductive Sterility Triggered by Dysbiosis of Intestinal Microorganisms

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Discussion

Implication

Cite This Study

Mechanisms of Male Reproductive Sterility Triggered by Dysbiosis of Intestinal Microorganisms

Key Points

Discussion

Implication

Cite This Study

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