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April 23, 2024Proceedings of the National Academy of SciencesOpen Access

Decorin suppresses tumor lymphangiogenesis: A mechanism to curtail cancer progression

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DMDipon Kumar MondalSidney Kimmel Cancer CenterCXChristopher XieSidney Kimmel Cancer CenterGPGabriel J. PascalThomas Jefferson University

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Cite This Study

Mondal et al. (2024) studied this question.

synapsesocial.com/papers/68e6de6eb6db64358765a688https://doi.org/10.1073/pnas.2317760121
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Decorin Evokes a Pro‐Lysosomal Pathway in Lymphatic Endothelial Cells2025 · 1 citations
  2. 2De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells.1995
  3. 3Decorin (DCN) Downregulation Activates Breast Stromal Fibroblasts and Promotes Their Pro-Carcinogenic Effects through the IL-6/STAT3/AUF1 Signaling2024 · 9 citations
  4. 4Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice2024 · 12 citations
  5. 5PDGF-Stimulated Corneal Keratocyte Motility and Migration Patterns on Aligned Collagen Fibrils Are Inhibited by Decorin2026