Frequency and geographical distribution of the use of sacubitril/valsartan in Colombia between 2019 and 2020

Introduction:Real-life adherence to the management of heart failure is suboptimal.Adherence to the recommendations for the use of sacubitril/valsartan in Colombia is unknown.Objective: To assess the frequency of use, geographic distribution, and demographic characteristics of patients who were prescribed sacubitril/valsartan in 2019-2020, using data from the "Sistema Integrado de Información de Protección Social" (SISPRO).Materials and method: This is a descriptive cross-sectional study.Information was extracted on the prescription distribution by department, gender, five-year age group and the ICD-10 codes with which the medication was prescribed.Results: Between 2019 and 2020, 23,026 patients in Colombia were prescribed sacubitril/valsartan; 63.86% of the patients were men.Ninety-two percent of the prescriptions were for patients over the age of 50.The regions of the country with the highest prescription frequency were Bogotá, Sucre and Santander.Conclusions: Taking into account the estimated prevalence of heart failure (2-3%), the frequency with which sacubitril/valsartan is prescribed in Colombia is lower than expected.The rural regions of the country have the lowest use, which suggests access barriers that should be explored.