Prospective observational study observes microbiome changes in children starting proton pump inhibitors, highlighting potential links to gastrointestinal and respiratory infections.
Proton pump inhibitor (PPI) use has been associated with an increased risk of gastrointestinal and upper respiratory infections in children. There are limited longitudinal data on the effect of PPI in children. The goal of this prospective observational study was to compare the stool and oropharyngeal microbiome of children before and after starting PPIs.
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Zhang et al. (2024) studied this question.
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