Unraveling marine bioactive compounds for oral cancer treatment

• Marine bioactive compounds have diverse mechanisms of action, such as their ability to induce apoptosis, modulate signaling pathways like PI3K/AKT, and generate reactive oxygen species. • Marine-derived compounds that are effective in cancer treatment, such as the depsipeptide thiocoraline found in Micromonospora marina and the cyanobacterial kinase inhibitors found in cyanobacteria. • Seaweed compounds are antioxidants and can be used to reduce tumor development by preventing abnormal cell transformations. • The use of marine bioactive compounds for the treatment of oral cancer is discussed, including chitosan, bio-adhesives, tissue regeneration gel, and algal extracts. • Highlight the potential role that marine bioactive compounds may play in improving conventional treatments, inhibiting angiogenesis, and revolutionizing cancer treatment if further research is conducted and collaboration is established.