Pd54-09 Evaluation of Nocturia in Patients Affected by Severe Obstructive Sleep Apnea Syndrome by Nocturnal Bladder Capacity Index

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Overactive Bladder II (PD54)1 May 2024PD54-09 EVALUATION OF NOCTURIA IN PATIENTS AFFECTED BY SEVERE OBSTRUCTIVE SLEEP APNEA SYNDROME BY NOCTURNAL BLADDER CAPACITY INDEX Antonio Luigi Pastore, Yazan Al Salhi, Manfredi Bruno Sequi, Paolo Pietro Suraci, Onofrio Antonio Rera, Fabio Maria Valenzi, Alice Antonioni, Giorgio Martino, Giuseppe Candita, Damiano Graziani, Silvio Scalzo, Filippo Gianfrancesco, Alessandro Sciarra, Ettore De Bernardinis, Antonio Cicione, Andrea Fuschi, Cosimo De Nunzio, Ettore De Bernardinis, and Antonio Carbone Antonio Luigi PastoreAntonio Luigi Pastore , Yazan Al SalhiYazan Al Salhi , Manfredi Bruno SequiManfredi Bruno Sequi , Paolo Pietro SuraciPaolo Pietro Suraci , Onofrio Antonio ReraOnofrio Antonio Rera , Fabio Maria ValenziFabio Maria Valenzi , Alice AntonioniAlice Antonioni , Giorgio MartinoGiorgio Martino , Giuseppe CanditaGiuseppe Candita , Damiano GrazianiDamiano Graziani , Silvio ScalzoSilvio Scalzo , Filippo GianfrancescoFilippo Gianfrancesco , Alessandro SciarraAlessandro Sciarra , Ettore De BernardinisEttore De Bernardinis , Antonio CicioneAntonio Cicione , Andrea FuschiAndrea Fuschi , Cosimo De NunzioCosimo De Nunzio , Ettore De BernardinisEttore De Bernardinis , and Antonio CarboneAntonio Carbone View All Author Informationhttps://doi.org/10.1097/01.JU.0001008724.35538.9c.09AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The Nocturnal Bladder Capacity Index (NBCi) is useful to distinguish nocturia caused by low bladder capacity from nocturnal polyuria. Obstructive sleep apnea syndrome (OSAS) is a common sleep-related breathing disorder. Moderate to severe OSAS affects 2%-14% of the general population. The NBCi is based on the difference between the "predicted" and actual number of night voids. The more the actual number of night voids exceeds the predicted night voids, the lower is night bladder capacity. The primary endpoint of this study was to evaluate the NBCi in subjects affected by severe OSAS as defined by the apnea–hypopnea index (AHI) <30. METHODS: This prospective study was conducted on a cohort of patients suffering from severe OSAS. All patients were studied with a full night polysomnography and all patients were asked to complete a 48-h frequency volume chart (FVC), including the time and volume of each void, bedtime, and time of rising. The FVC provided details regarding the actual number of nightly voids (ANV), nocturnal urine volume (NUV), and maximum voided volume (MVV; i.e., bladder capacity). These data were used to calculate the nocturnal bladder capacity index (NBCi). An unrounded NBCi calculation {ANV − [(NUV/MVV) − 1]} was used, with a cut-off value of 1.3, higher values indicate reduced bladder capacity as a cause of nocturia. RESULTS: In total, 75 eligible patients were identified (mean age 67 years; 57 males, 18 females) and enrolled in the study. The mean AHI was 28.9 (range 27.3-29.2). In all patients the NBCi was above 1.3, with a mean value of 1.43, without significant differences between the two sex (M=1.45 and F=1.42). The mean ANV was 4.1, the mean NUV was 825.6 mL, the mean nocturnal bladder capacity (maximal voided volume at night) was 264.2 mL. Surprisingly, no significant differences were observed between male and female patients. The AHI was significantly correlated with the value of NBCi >1.3, p<0.001. CONCLUSIONS: Nocturia and OSAS are two syndromes that seriously impact patients' quality of life. Severe OSAS (AHI <30) are significantly related with reduced bladder capacity as a cause of nocturia (NBCi >1.3). Further studies are needed to better establish the correlation of nocturia and OSAS, in order to understand whether a possible common pathway might support both syndromes. Source of Funding: Di Bello F, Napolitano L, Abate M, Collà Ruvolo C, Morra S, Califano G, Capece M, Creta M, Scandurra C, Muzii B, Di Nola C, Bochicchio V, Nocini R, Abbate V, Maldonato NM, Dell'Aversana Orabona G, Longo N, Cantone E. "Nocturia and obstructive sleep apnea syndrome: A systematic review". Sleep Med Rev. 2023 Jun;69:101787. doi: 10.1016/j.smrv.2023.101787. Epub 2023 Apr 29. PMID: 37167825 © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1147 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Antonio Luigi Pastore More articles by this author Yazan Al Salhi More articles by this author Manfredi Bruno Sequi More articles by this author Paolo Pietro Suraci More articles by this author Onofrio Antonio Rera More articles by this author Fabio Maria Valenzi More articles by this author Alice Antonioni More articles by this author Giorgio Martino More articles by this author Giuseppe Candita More articles by this author Damiano Graziani More articles by this author Silvio Scalzo More articles by this author Filippo Gianfrancesco More articles by this author Alessandro Sciarra More articles by this author Ettore De Bernardinis More articles by this author Antonio Cicione More articles by this author Andrea Fuschi More articles by this author Cosimo De Nunzio More articles by this author Ettore De Bernardinis More articles by this author Antonio Carbone More articles by this author Expand All Advertisement PDF downloadLoading ...