MP27-06 RESULTS FROM A MULTICENTER PROSPECTIVE STUDY ON THE IMPACT OF AGE ON FUNCTIONAL OUTCOMES AFTER IMPLANTATION OF A SECOND-GENERATION NITINOL TEMPORARY DEVICE (iTIND) FOR THE TREATMENT OF BPH-RELATED LUTS

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II (MP27)1 May 2024MP27-06 RESULTS FROM A MULTICENTER PROSPECTIVE STUDY ON THE IMPACT OF AGE ON FUNCTIONAL OUTCOMES AFTER IMPLANTATION OF A SECOND-GENERATION NITINOL TEMPORARY DEVICE (iTIND) FOR THE TREATMENT OF BPH-RELATED LUTS Sabrina Titti De Cillis, Daniele Amparore, Martin Schönthaler, Grégoire Robert, Francesco Cantiello, Fernando Gómez Sancha, Andreas Becker, Piero Tognoni, Cosimo De Nunzio, Gautier Muellhaupt, Nicolas Barry Delongchamps, Emanuel Della Negra, Henry Who, and Francesco Porpiglia Sabrina Titti De CillisSabrina Titti De Cillis , Daniele AmparoreDaniele Amparore , Martin SchönthalerMartin Schönthaler , Grégoire RobertGrégoire Robert , Francesco CantielloFrancesco Cantiello , Fernando Gómez SanchaFernando Gómez Sancha , Andreas BeckerAndreas Becker , Piero TognoniPiero Tognoni , Cosimo De NunzioCosimo De Nunzio , Gautier MuellhauptGautier Muellhaupt , Nicolas Barry DelongchampsNicolas Barry Delongchamps , Emanuel Della NegraEmanuel Della Negra , Henry WhoHenry Who , and Francesco PorpigliaFrancesco Porpiglia View All Author Informationhttps://doi.org/10.1097/01.JU.0001009400.86696.a2.06AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The aim of this European study was assessing the impact of age on postoperative micturition outcomes after second generation iTIND for the treatment of Benign Prostatic Hyperplasia (BPH)-related LUTS. METHODS: From 6/2018 to 9/2019 men with symptomatic BPH (International Prostate Symptoms Score (IPSS) ≥10, maximum flow rate (Qmax) <12 ml/s and prostate volume <120 ml) were enrolled in this single-arm, prospective multicenter study and underwent iTIND implantation. Demographics and baseline IPSS, QoL, Qmax and post voiding residue (PVR) were recorded. Follow-up was conducted via IPSS, QoL, Qmax and PVR assessed at 1, 3, 6 and 12 months post-operatively. For the purpose of the study patients were stratified into 3 age groups (group 1<50 yrs (not approved in US); group 2 50-69 yrs; group 3 70+ yrs) and the postoperative functional outcomes evaluated accordingly. RESULTS: 149 patients enrolled, 115 reached the 12 months follow up and were included in this analysis. Overall baseline mean (SD) IPSS, IPSS-QoL, Qmax and PVR were 20.8 (5.7), 4.1 (1.0), 8.1 (2.4) and 75.2 (86.5), respectively. At 12 months follow-up a statistically significant (p<0.001) improvement of micturition variables was recorded, reaching values of 10.0 (7.4) points for IPSS, 1.8 (1.5) for IPSS QoL, 11.7 (4.5) ml/s for Qmax and 46.0 (54.5) ml for PVR. After stratification based on age 22, 97 and 30 patients were included in group 1, group 2 and group 3. Demographics and baseline characteristics were comparable between the groups. Post implantation functional outcomes were significantly ameliorated from baseline in all groups at each follow-up timepoint (p<0.001). No statistically significant difference was encountered between groups in terms of IPSS, IPSS-QoL and PVR at each follow-up (p>0.05). Postoperative Qmax values of group 3 were lower than those reported by groups 1 and 2 at all time intervals (Figure 1), although even this difference was not statistically significant (p>0.05). CONCLUSIONS: Implantation of iTind is an effective treatment for BPH-related LUTS in patients of all age groups. Although significantly improved compared to baseline, lower Qmax values should be expected in patients aged >70 years compared to their younger counterparts. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e425 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Sabrina Titti De Cillis More articles by this author Daniele Amparore More articles by this author Martin Schönthaler More articles by this author Grégoire Robert More articles by this author Francesco Cantiello More articles by this author Fernando Gómez Sancha More articles by this author Andreas Becker More articles by this author Piero Tognoni More articles by this author Cosimo De Nunzio More articles by this author Gautier Muellhaupt More articles by this author Nicolas Barry Delongchamps More articles by this author Emanuel Della Negra More articles by this author Henry Who More articles by this author Francesco Porpiglia More articles by this author Expand All Advertisement PDF downloadLoading ...