Mp27-10 Multicenter Study Evaluating the Safety and Feasibility of Transurethral Intraprostatic Injections of Anesthetics (Tuia) Delivered via Schelin Catheter Tm to Perform Minimally Invasive Surgical Techniques for Benign Prostatic Obstructions

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II (MP27)1 May 2024MP27-10 MULTICENTER STUDY EVALUATING THE SAFETY AND FEASIBILITY OF TRANSURETHRAL INTRAPROSTATIC INJECTIONS OF ANESTHETICS (TUIA) DELIVERED VIA SCHELIN CATHETERTM TO PERFORM MINIMALLY INVASIVE SURGICAL TECHNIQUES FOR BENIGN PROSTATIC OBSTRUCTIONS Silvia Secco, Alberto Olivero, Francesco Sessa, Luca Cindolo, Ka Fung Peter Chiu, Michael Baboudjian, Mattia Sibona, Mattia Lo Re, Eric Lechevallier, Paolo Destefanis, Paolo Dell'Oglio, Stefano Tappero, Francesco Chierigo, Ofir Maltzman, Alberto Caviglia, Erika Palagonia, Carlo Buratto, Aldo Massimo Bocciardi, Antonio Galfano, Mauro Gacci, and Giampaolo Siena Silvia SeccoSilvia Secco , Alberto OliveroAlberto Olivero , Francesco SessaFrancesco Sessa , Luca CindoloLuca Cindolo , Ka Fung Peter ChiuKa Fung Peter Chiu , Michael BaboudjianMichael Baboudjian , Mattia SibonaMattia Sibona , Mattia Lo ReMattia Lo Re , Eric LechevallierEric Lechevallier , Paolo DestefanisPaolo Destefanis , Paolo Dell'OglioPaolo Dell'Oglio , Stefano TapperoStefano Tappero , Francesco ChierigoFrancesco Chierigo , Ofir MaltzmanOfir Maltzman , Alberto CavigliaAlberto Caviglia , Erika PalagoniaErika Palagonia , Carlo BurattoCarlo Buratto , Aldo Massimo BocciardiAldo Massimo Bocciardi , Antonio GalfanoAntonio Galfano , Mauro GacciMauro Gacci , and Giampaolo SienaGiampaolo Siena View All Author Informationhttps://doi.org/10.1097/01.JU.0001009400.86696.a2.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The Schelin catheterTM (SC) is a device for injections of drugs into the prostate that has recently become available and is used to decrease the invasiveness of minimally invasive surgical treatments (MISTs) for BPH-related LUTS. In this multicenter study, we aimed to evaluate the safety and feasibility of transurethral intraprostatic anesthesia (TUIA) through SC and procedural and post-procedural pain levels for patients treated with RezumTM or iTINDTM. METHODS: We collected data from 59 patients who underwent RezumTM and four treated with iTINDTM in 6 referral centers from September 2022 to October 2023. Procedures were performed in conscious sedation (2 mg midazolam ev) and local prostatic anesthesia through the SC, injecting mepivacaine 3% or lidocaine 1% into the gland, according to the following scheme: 3–2–2 mL at 8 and 4 o'clock position; 3 ml at 10 and 2 o'clock position. After injections, the SC removed. The pain rate was measured using a numeric range scale (NRS) from 0-10 at eight different time points. We divided the pain scores into three groups: mild 0-3, moderate 4-6, and severe 7-10. We considered each step successfully performed if the reported pain during the steps was mild. RESULTS: The median NRS reported for each timepoint is shown in the Table. No procedure needed a switch to other forms of anesthesia. No perioperative and procedure-related complications to the use of SC were reported. The rate of success was >80% in all the measured steps. In the patients who experienced moderate and severe pain, an increase in EV sedation (1 mg midazolam +/- 10 mg pethidine) was sufficient to complete the procedure. CONCLUSIONS: This multicenter series demonstrates that transurethral intraprostatic anesthesia through SC can control pain during Rezum treatment and iTIND. Our data suggest the procedure is feasible, safe and well-tolerated. According to our preliminary data and experience, TUIA allows a further step towards micro-invasiveness. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e427 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Silvia Secco More articles by this author Alberto Olivero More articles by this author Francesco Sessa More articles by this author Luca Cindolo More articles by this author Ka Fung Peter Chiu More articles by this author Michael Baboudjian More articles by this author Mattia Sibona More articles by this author Mattia Lo Re More articles by this author Eric Lechevallier More articles by this author Paolo Destefanis More articles by this author Paolo Dell'Oglio More articles by this author Stefano Tappero More articles by this author Francesco Chierigo More articles by this author Ofir Maltzman More articles by this author Alberto Caviglia More articles by this author Erika Palagonia More articles by this author Carlo Buratto More articles by this author Aldo Massimo Bocciardi More articles by this author Antonio Galfano More articles by this author Mauro Gacci More articles by this author Giampaolo Siena More articles by this author Expand All Advertisement PDF downloadLoading ...