Mp12-07 the Relationship Between Frailty and Instrumental Activities of Daily Living and Its Impact on Quality-of-Life in Patients With Urological Cancers

You have accessJournal of UrologyHealth Services Research: Practice Patterns, Quality of Life and Shared Decision Making I (MP12)1 May 2024MP12-07 THE RELATIONSHIP BETWEEN FRAILTY AND INSTRUMENTAL ACTIVITIES OF DAILY LIVING AND ITS IMPACT ON QUALITY-OF-LIFE IN PATIENTS WITH UROLOGICAL CANCERS Fumiya Yoneyama, Shingo Hatakeyama, Osamu Soma, Yusuke Ozaki, Takuma Narita, Naoki Fujita, Teppei Okamoto, Hayato Yamamoto, Takahiro Yoneyama, Yasuhiro Hashimoto, and Chikara Oyama Fumiya YoneyamaFumiya Yoneyama , Shingo HatakeyamaShingo Hatakeyama , Osamu SomaOsamu Soma , Yusuke OzakiYusuke Ozaki , Takuma NaritaTakuma Narita , Naoki FujitaNaoki Fujita , Teppei OkamotoTeppei Okamoto , Hayato YamamotoHayato Yamamoto , Takahiro YoneyamaTakahiro Yoneyama , Yasuhiro HashimotoYasuhiro Hashimoto , and Chikara OyamaChikara Oyama View All Author Informationhttps://doi.org/10.1097/01.JU.0001009376.16371.fb.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: While frailty and instrumental activities of daily living (IADL) are closely related, the correlation between the two has not been sufficiently explored. Moreover, the impact of frailty on the health-related quality-of-life (QOL) remains unknown. We investigated the relationship between frailty and IADL and the impact of frailty on QOL decline in patients with urological cancers. METHODS: We retrospectively evaluated 1992 patients with urological cancers who initially presented as outpatients in our hospital between January 2017 and November 2022. We evaluated frailty and IADL using the Geriatric 8 (G8) and Tokyo Metropolitan Institute of Gerontology Index of Competence (TMIG). A global QOL was evaluated by the QLQ-C30. The primary outcome was the TMIG cutoff setting corresponding to the G8≤14 and percentage of agreement. Secondary outcomes included the effect of frailty on poor global QOL in patients with urological cancers. RESULTS: Of 1992 patients, median G8, and TMIG were 14 and 12, respectively. The association of G8 and TMIG was moderate (R=0.482). The TMIG cutoff value corresponding to G8≤14 was<11 with an agreement of 57.7%. Multivariable logistic regression analysis showed that G8≤14, TMIG<11, and metastatic disease were significantly associated with global QOL≤50%. Patients who met the two criteria (G8≤14 and TMIG<11) had a higher rate of poor global QOL in both nonmetastatic (65.4%) and metastatic diseases (73.7%). CONCLUSIONS: We found the TMIG value corresponding to G8≤14 was<11 with an agreement of 57.7%. Accumulation of frailty is significantly associated with poor global QOL at baseline. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e202 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Fumiya Yoneyama More articles by this author Shingo Hatakeyama More articles by this author Osamu Soma More articles by this author Yusuke Ozaki More articles by this author Takuma Narita More articles by this author Naoki Fujita More articles by this author Teppei Okamoto More articles by this author Hayato Yamamoto More articles by this author Takahiro Yoneyama More articles by this author Yasuhiro Hashimoto More articles by this author Chikara Oyama More articles by this author Expand All Advertisement PDF downloadLoading ...