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Experimental study demonstrates that WHAMM directs actin polymerization for kidney reabsorption in mice, highlighting essential roles in autophagosomal membrane closure.
The actin cytoskeleton is essential for many functions of eukaryotic cells, but the factors that nucleate actin assembly are not well understood at the organismal level or in the context of disease. To explore the function of the actin nucleation factor WHAMM in mice, we examined how
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Coulter et al. (2024) studied this question.
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