Effects of EDG-5506, a Fast Myosin Modulator, on Function and Biomarkers of Muscle Damage in Adults with Becker Muscular Dystrophy (S21.002)

H. Phan; Samuel Collins; Alan J. Russell; Ben Barthel; Liz Thaler; Nicole Kilburn; Maria Mancini; James E. MacDougall; Joanne M. Donovan

doi:10.1212/wnl.0000000000206199

April 9, 2024Neurology

Effects of EDG-5506, a Fast Myosin Modulator, on Function and Biomarkers of Muscle Damage in Adults with Becker Muscular Dystrophy (S21.002)

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Key Points

Treatment with EDG-5506 is evaluated to protect muscle function and lower biomarkers of muscle damage in adults with Becker muscular dystrophy.
Assessment protocols examine changes in circulating muscle damage biomarkers and functional capacity, focusing on targeted motor improvements.
Investigating fast myosin modulator therapy highlights opportunities to address muscular dystrophy, offering insight into muscle fiber protection.

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Implication

Clinical assessment observes the effects of EDG-5506 on muscle damage and physical function in adults with Becker muscular dystrophy, suggesting potential therapeutic benefit.

Abstract

Assess the effect of treatment with EDG-5506 on biomarkers of muscle damage and function in adults with Becker Muscular Dystrophy.

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Phan et al. (2024) studied this question.

synapsesocial.com/papers/68e6fcafb6db643587676c36 https://doi.org/10.1212/wnl.0000000000206199

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Effects of EDG-5506, a Fast Myosin Modulator, on Function and Biomarkers of Muscle Damage in Adults with Becker Muscular Dystrophy (S21.002)

Key Points

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Implication

Abstract

Discussion

Cite This Study

Effects of EDG-5506, a Fast Myosin Modulator, on Function and Biomarkers of Muscle Damage in Adults with Becker Muscular Dystrophy (S21.002)

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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