Acrania is a rare congenital anomaly and characterized by partial or complete absence of the calvarium. Although acrania associated with anencephaly is a well-recognized entity but isolated acrania is a rare anomaly. Ultrasound allows early diagnosis of this anomaly. The fetus was found to have a completely formed brain, base of the skull and facial structures but lacking a cranium. Authors present a rare case of acrania. Journal of National Institute of Neurosciences Bangladesh, July 2023;9(2):157-160
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