Prevalence of Vitamin - D Deficiency in Coronary Artery Disease and its Co - Relation with Angiographic Severity

Coronary Artery Disease (CAD) is a global public health concern, contributing significantly to morbidity, disability, and mortality. Ischemic heart disease accounts for a notable portion of deaths worldwide, with a higher prevalence in well -developed countries. Lifestyle factors play a pivotal role in the development of cardiovascular diseases like CAD, which primarily stem from atherosclerosis in the coronary arteries. Traditional risk factors include age, cholesterol levels, blood pressure, and smoking while emerging research suggests a potential link between vitamin D deficiency and increased CAD risk, although supplementation benefits remain inconclusive. A prospective observational study spanning six months was conducted at Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, India. Forty -seven eligible patients aged 18 -75, referred for Coronary Angiogram, were recruited. Exclusion criteria included chronic kidney disease and disorders affecting the Parathormone -Vitamin D axis. Analysis using SPSS Software Version 2.1 revealed no correlation between age and vitamin D levels. The study population exhibited an average vitamin D level indicative of insufficiency, aligning with previous Indian angiographic studies. Specifically, 80% of patients undergoing angiograms demonstrated insufficient vitamin D levels. These findings underscore the significant prevalence of vitamin D insufficiency in high -risk populations undergoing coronary angiograms, highlighting the potential for supplementation intervention.