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April 1, 2024Cell ReportsOpen Access

Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration

Kevin MingJie Gao Kristy Chiang Zhaozhao Jiang F.T. Korkmaz Harish P. Janardhan Chinmay M. Trivedi Lee J. Quinton Sébastien Gingras Katherine A. Fitzgerald Ann Marshak‐Rothstein

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Abstract

Patients afflicted with Stimulator of interferon gene (STING) gain-of-function mutations frequently present with debilitating interstitial lung disease (ILD) that is recapitulated in mice expressing the STING

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Cite This Study

Gao et al. (2024) studied this question.

synapsesocial.com/papers/68e70d8cb6db64358768709c https://doi.org/10.1016/j.celrep.2024.114114

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