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October 9, 2025Open Access

A complex network perspective on brain disease

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Authors

DPDavid PapoJBJavier M. Buldú

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Overview

Discussion reveals how complex network structures influence brain function and pathology, suggesting clinical implications.

Key Points

  • Network structure plays a crucial role in both brain function and dysfunction, impacting disease outcomes.
  • The definition of disease is related to the concept of function, influencing the relevance of network properties in brain disease.
  • Characterizing brain pathology through a network lens may enhance understanding of recovery likelihood and vulnerability.
  • Investigating 'networkness' in brain disease can provide insights into functional brain activity and potential clinical utilities.

Cite This Study

Papo et al. (2025) studied this question.

synapsesocial.com/papers/68e7103b90569dd607ee69eehttps://doi.org/10.48550/arxiv.2507.23678
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  4. 4Advanced complex networks methods for brain structure-function analysis2025
  5. 5Clinical connectomics: Mapping structural brain networks in disease2026 · 4 citations