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May 1, 2026Scientific ReportsOpen Access

Telecommunication-inspired network models of healthy and diseased brains

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Authors

PFPeppino FazioMMMaria MannoneNMNorbert Marwan

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Overview

Randomized trial maps neuronal behaviors and connectivity in the brain, revealing implications for disease understanding.

Key Points

  • The study aims to explore how diseases impact neuron connectivity and behaviors within the brain using advanced modeling techniques.
  • Applied a discrete finite-state model to understand neuronal agglomerates.
  • Compared brain behavior to a wireless clustered network.
  • Analyzed inter-cluster communications under conditions of temporal variations and degradation.
  • Demonstrated altered neuronal behaviors in diseased states compared to healthy models.
  • Found that disease significantly disrupts the connectivity between neuronal agglomerates.
  • Revealed important insights into the application of routing theory for understanding brain function.

Cite This Study

Fazio et al. (2026) studied this question.

synapsesocial.com/papers/69f44223967e944ac5565ef7https://doi.org/10.1038/s41598-026-50758-x
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