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Case report describes macrophage activation syndrome leading to acute tubular necrosis, highlighting inflammatory response implications.
Macrophage activation syndrome (MAS) is a severe, potentially fatal condition associated with excessive activation and expansion of macrophages and T cells (mainly CD8), leading to exaggerated inflammatory response. We describe here a case of MAS causing possibly ATN and review the literature.
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Rehman et al. (2021) studied this question.
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