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This is a Quantitative Study study.

October 9, 2025Advances in Bioengineering

The Regulation of Adhesion Molecule Expression by Fluid Shear Stress in Human Vascular Endothelial Cells

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Authors

DCDavid C. ChappellUniversity of West London RAR. Wayne AlexanderGeneral / Preventive / Lipids RMRussell M. MedfordOSRAM (United States)

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Implication

Observational analysis shows shear stress affects adhesion molecule expression in endothelial cells, indicating implications for atherosclerosis progression.

Key Points

Moderately high shear stress significantly influences the expression of adhesion molecules in endothelial cells.
The study demonstrates that oscillating shear stress affects the binding of monocytes to the endothelium, a key event in atherogenesis.
Human umbilical vein endothelial cells were analyzed under varying shear stress conditions to assess changes in adhesion molecule expression.
These findings may enhance understanding of how localized shear stress contributes to the development of atherosclerosis.

Cite This Study

Chappell et al. (1995) studied this question.

synapsesocial.com/papers/68e7103e90569dd607ee6f0a https://doi.org/10.1115/imece1995-0196

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Implication

Observational analysis shows shear stress affects adhesion molecule expression in endothelial cells, indicating implications for atherosclerosis progression.

The Regulation of Adhesion Molecule Expression by Fluid Shear Stress in Human Vascular Endothelial Cells

Discussion

Member takes

Implication

Key Points

Cite This Study

The Regulation of Adhesion Molecule Expression by Fluid Shear Stress in Human Vascular Endothelial Cells

Discussion

Member takes

Implication

Key Points

Cite This Study

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