Wcn24-2404 Thrombotic Microangiopathy as Cause of Renal Graft Dysfunction in Patient With Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus and Response to B-Cell Activating Factor Inhibitor

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by persistently positive antiphospholipid antibodies (aPL) associated with thrombosis (arterial or venous) or recurrent pregnancy loss. Clinical presentation spectrum ranges from venous thrombosis to multiorgan involvement in catastrophic antiphospholipid syndrome (CAPS), with a minority of patients experiencing microvascular thrombosis. Thrombosis risk increases based on the subtype and number of APS present, with