Сalcineurin inhibitors (CNI) is currently being considered as the first line immunosuppressive treatment for steroidresistant nephrotic syndrome (SRNS) in children. However, CNI-induced nephrotoxicity is potential adverse effect of the treatment. The aim of the study was to identify risk factors for progression from acute to chronic CNI-induced nephrotoxicity in children with SRNS due to FSGS.
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Khokhlova et al. (2024) studied this question.
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