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Severe COVID-19 disease can be associated with an increased catabolic state resulting in hyperuricemia (HyperAU) and high creatine kinase (HyperCK). HyperAU and Hyper CPK could increase the risk for severe Acute Kidney Injury (AKI) defined by KDIGO as stages 2 and 3. The main purpose of this research project is to analyze hyperuricemia (HyperAU) and high creatin kinase (Hyper CPK) as risk factors for severe AKI development in a cohort of severe COVID-19 patients.
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Aleman et al. (2024) studied this question.
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