Comparison of three different dental implant biological coating techniques

Introduction: Titanium alloy (Ti–6Al–4V) surface coating with the amino acid RGD peptide was found to improves the adhesion of osteoblasts to the implant surface. This work aimed at comparing three different methods to immobilize the amino acid sequence RGD to the Ti–6Al–4V. Materials and methods: This article tested three different methods to immobilize the amino acid sequence RGD to Ti–6Al–4V) implants surface, the first method used alkane phosphonic acid and maleimide as coupling factor, the second method used a simple dip-in technique and dehydration, and the third method used a collagen coating to which the RGD was linked, then the resulting coatings were tested using the Fourier Transform Infrared (FT-IR) spectroscopy, and surface binding energy.Results: The FT-IR and surface binding energy indicated the first method yielded better and stronger RGD coating.Conclusion: The titanium alloy chemical coating process of the amino acid sequence RGD was found to yield better results ac compare to the dip-in and RGD-collagen linking methods.