Observation of Chemical Shift in Hyperpolarized ¹²⁹Xe Gas Dissolution under Low Magnetic Field of 0.3 T

Due to the increasing number of patients with chronic obstructive pulmonary disease (COPD) and lung cancer, the use of low-field MRI (magnetic resonance imaging) is attracting attention. Low-field MRI is less expensive and safer than high-field MRI. It is also possible to obtain high-sensitivity images using "hyperpolarization" of certain gases (eg 129Xe gas). In this study, we aimed to develop lung field imaging technology by low-field MRI of 0.3 T using hyperpolarized 129Xe gas, and observed chemical shifts in saline and porcine blood. As a result, it is expected to expand the possibility of high-sensitivity imaging diagnosis in a low magnetic field of 0.3 T and contribute to a new understanding of hyperpolarized 129Xe gas, and the practical application of these technologies is expected.