By placing a medication plan into healthy, unblemished skin, the Transdermal Drug Delivery System (TDDS) is a simple method of delivering medications topically. The drug enters through the cuticle and then passes through the epidermis and dermis without entering the drug, primarily concentrating in the dermal layer. The use of microneedles for transdermal medicine delivery is becoming more and more popular due to problems associated with oral medication delivery methods. The medication's digestive tract exposes it to corrosive and catalytic substances found in the stomach, which causes the compound to denaturate and results in low bioavailability. This review focuses solely on the accessible literature from the past ten years in order to assess the various fabrication techniques, provide an update on the progress made in the creation of polymeric MNs, discuss the difficulties encountered in the process, and assess the potential uses of polymeric MNs in the healthcare industry. Microneedles are regarded as sturdy.
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Balusupati et al. (2024) studied this question.
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