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March 27, 2024Genome MedicineOpen Access

Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes

Mohammad Amin Honardoost Andreas Adinatha Florian Schmidt Bobby Ranjan Maryam Ghaeidamini Nirmala Arul Rayan Michelle Gek Liang Lim Ignasius Joanito Quy Xiao Xuan Lin Deepa Rajagopalan Shi Qi Mok You Yi Hwang Anis Larbi Chiea Chuen Khor Roger Foo Bernhard O. Boehm Shyam Prabhakar

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Abstract

Type 1 diabetes mellitus (T1DM) is a prototypic endocrine autoimmune disease resulting from an immune-mediated destruction of pancreatic insulin-secreting

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Honardoost et al. (2024) studied this question.

synapsesocial.com/papers/68e720ddb6db64358769af54 https://doi.org/10.1186/s13073-024-01300-z

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