Follicular lymphoma (FL) constitutes nearly 30% of all lymphomas, making it the second most prevalent B-cell lymphoma. It exhibits an indolent course within the spectrum of non-Hodgkin lymphoma, with variable 5-year progression-free survival rates. Histologically graded 1–3, FL primarily affects bone marrow and lymphoid organs but may also involve extranodal tissues, such as bilateral muscle tissue. This report outlines the diagnostic challenges associated with disease recurrence in such unusual locations, emphasizing the need for vigilance among clinicians and radiologists. Through imaging and biopsy, we confirmed recurrence in the patient. The study highlights the role of 18F-FDG PET/CT in detecting uncommon FL sites and guiding treatment decisions while emphasizing the importance of multidisciplinary care for optimal patient management.
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Oliveti et al. (2024) studied this question.
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