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March 22, 2024Cancer Research

Abstract 5992: Expression of oncogenic ASSP2k in acute myeloid leukemia directly contributes to resistance to therapy and aggressiveness of the disease

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Authors

ARAlessia RuibaMSMarcus M. SchittenhelmAAAnna Lena Ahrens

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Ruiba et al. (2024) studied this question.

synapsesocial.com/papers/68e72ce8b6db6435876a6fa3https://doi.org/10.1158/1538-7445.am2024-5992
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oncogenic ASPP2κ: A novel regulator of drug resistance and tumor progression in multiple myeloma2025
  2. 2Abstract 6149: Oncogenic ASPP2 <i>kappa</i> exerts a regulatory role within the tumor microenvironment and promotes metastasis in TNBC models2026
  3. 3Abstract P33: High-throughput Transcriptomics Identifies Chemoresistance-associated Gene Expression Signatures in Human Angiosarcoma2025
  4. 4Abstract 4717: Small molecule modulation of PP2A selectively induces oncogenic cytotoxicity through chronic and irreversible integrated stress response2024
  5. 5Enhancing ASPP2 promotes acute liver injury via an inflammatory immunoregulatory mechanism2024