Abstract 6986: Oncogenic CARD11 enhances marginal zone B cell survival by potentiating the non-canonical NF-κB pathway

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1P06.01 Gain-of-function CARD11 signalling in B cells causes pathological lymphoproliferative disease in mice which is strictly dependent on MALT1 activity2024
2. 2Autonomous BCR signaling and the CARD11 L251P mutation as alternative oncogenic drivers induce identical gene expression profiles in genetically engineered ABC-DLBCL models2025
3. 3Deleterious germline CARD11 gain-of-function variants alter human B-cell and CD4+ T-cell differentiation and function2026
4. 4Abstract A009: PKCδ-mediated feedback control of B-cell receptor signaling and its subversion in diffuse large B-cell lymphoma2026
5. 5Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB2024 · 8 citations