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March 22, 2024Cancer Research

Insulin-Like Growth Factor Receptor Predicts Poor Prognosis in Early Non-Small Cell Lung Cancer

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Authors

HNHiroaki NagamineMYMasakazu YashiroMMMegumi Mizutani

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Overview

Retrospective cohort study demonstrates that insulin like growth factor receptor predicts worse survival in early-stage non small cell lung cancer, highlighting its utility as a prognostic marker.

Key Points

  • Elevated insulin like growth factor receptor expression independently predicts reduced recurrence free survival in early-stage non small cell lung cancer after resection.
  • Decade-long overall survival dropped to 54.4% compared to 67.3% in patients exhibiting positive insulin like growth factor receptor immunohistochemical staining.
  • Retrospective cohort analysis of 782 surgical specimens highlights insulin like growth factor receptor as a prognostic biomarker that may guide early-stage lung cancer care.

Cite This Study

Nagamine et al. (2024) studied this question.

synapsesocial.com/papers/68e72e3ab6db6435876a807fhttps://doi.org/10.1158/1538-7445.am2024-3635
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