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March 22, 2024Cancer Research

Abstract 39: Preclinical in vitro and in vivo evaluation of CD8αβ+ CD19 CAR iPSCs T cells generated in a TCR signal-independent manner using DLL4/VCAM-coupled microbeads

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Authors

MBMuluken S. BelewRCRichard L. CarpenedoAPAlessia Pallaoro

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Cite This Study

Belew et al. (2024) studied this question.

synapsesocial.com/papers/68e72f4bb6db6435876a8799https://doi.org/10.1158/1538-7445.am2024-39
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 11: Development of innovative off-the-shelf cancer immunotherapies with iPSC-derived CD8-positive T-cells2024 · 1 citations
  2. 2Engineering Intracellular Signaling Domains to Drive CAR-T Cell Differentiation from Pluripotent Stem Cell 28652025
  3. 3Abstract 36: The discovery of a novel CD19xCD22 dual-targeting CAR for the development of an IPSC-derived cell therapy2024
  4. 4Abstract LB313: Advancing iPSC derived CAR NK cell therapy for enhanced solid tumor treatment2026
  5. 5Abstract 661: Rapid CAR T testing in an ex vivo platform that maintains passage-zero patient tumor tissues and their native immunosuppressive microenvironment.2026